The latest statistics show that 10.7% or 6.5 million Americans (65 and over) are living with Alzheimer’s disease in 2022. That is about 1 in 9 people, and it is expected to double by 2050. Every 65 seconds, one person in the US is diagnosed with Alzheimer’s disease and almost two-thirds of them are women. The reasons for this are too complex for this one newsletter, but I want to address one cause – Medications. There are three classifications of drugs that can have this effect on our brains. 

1. Anti-cholinergic medications 2. Benzodiazepines and 3. Opioids. 

Acetylcholine

Before discussing anti-cholinergic medications, understanding what acetylcholine is helpful. It is a neurotransmitter, which means it is a chemical that nerve cells use to communicate with in the brain and in the rest of the body. It is important for memory and for the parasympathetic nervous system. The Autonomic Nervous System is made up of two parts the sympathetic nervous system which has an excitatory effect on us, and the parasympathetic nervous system that has a relaxing effect on us. The parasympathetic is referred to as the “rest and digest” part of the nervous system. The parasympathetic nervous system by way of acetylcholine release is going to help with digestion, saliva production and tear production for the eyes. Therefore, taking a medication that interferes with acetylcholine could result in constipation, dry mouth, and dry eyes. Those medications will also decrease brain function and make you feel sleepy. The following are medications that should be a red flag if you are taking them on a regular basis, especially if you are a senior citizen...